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Glue-Based Varicose Vein Treatment: Safety & Results

Varicose veins — those enlarged, twisted veins often seen on the legs — are more than just a cosmetic concern. They can cause aching, swelling, heaviness, skin changes, and in severe cases, ulcers or clots. For many years, treatment options involved surgery or heat-based procedures like Endovenous Laser Ablation (EVLA) and Radiofrequency Ablation (RFA).

In recent years, glue-based varicose vein treatment, also called cyanoacrylate closure, has emerged as a modern, minimally invasive option. But is it safe? Let’s explore what it is, how it works, and what patients need to know.

How Glue-Based Treatment Works

The procedure uses a specially formulated medical adhesive delivered into the diseased vein via a thin catheter, guided by ultrasound. Once inside, the glue seals the vein walls together. Blood flow is instantly rerouted to healthy veins, and over time, the closed vein is absorbed naturally by the body.

Because it doesn’t use heat, glue closure avoids thermal injury to surrounding tissues and eliminates the need for multiple injections of tumescent anaesthesia along the vein. Most treatments take 20–30 minutes per vein, with patients walking out of the clinic shortly after.

Key Benefits of Glue-Based Treatment

  1. Virtually Pain-Free

A single tiny numbing injection is usually all that’s needed. Patients often describe the experience as “more comfortable than a blood test.”

  1. Same-Day Return to Routine

Whether you have a desk job, run a business, or manage a household, you can get treated in the morning and resume normal activities the very same day.

  1. No Extended Stocking Wear

In India’s warm climate, avoiding weeks of compression stockings is a major relief. In many glue cases, stockings are either not required or needed for just a short period.

  1. Small, Cosmetic-Friendly Entry Point

No surgical cuts or stitches — just a tiny puncture that typically heals without a visible mark.

  1. Works for Many Patient Profiles

Suitable for a wide range of vein anatomies, including those where a no-heat approach is preferred. It’s an excellent addition to the treatment choices available in India.

Is It Safe?

Glue-based closure is FDA-approved and has been used globally since 2011. The adhesive is a proven surgical material also used in closing wounds and controlling bleeding in delicate surgeries. When performed by trained vascular specialists under ultrasound guidance, it has an excellent safety record.

Potential Risks

While uncommon, mild inflammation (phlebitis), temporary tenderness, or rare allergic reactions to the adhesive can occur. These usually resolve quickly with simple medication.

Results You Can Expect

  • Treated veins gradually shrink and fade over weeks to months
  • Noticeable relief from heaviness, swelling, and discomfort within days
  • Long-lasting closure and improved leg appearance with minimal downtime

The Bottom Line

Glue-based varicose vein treatment is a safe, comfortable, and highly effective option for those seeking a quick recovery and lasting results. It complements other advanced treatments like EVLA and RFA, ensuring patients have choices tailored to their needs.

Glue vs Laser vs RFA: Best Varicose Vein Treatment?

Varicose veins are more than a cosmetic issue — they are a medical condition that can cause aching, heaviness, swelling, cramps, skin discolouration, and, in advanced cases, ulcers or blood clots. If left untreated, the symptoms can worsen, affecting both health and quality of life.

The good news is that modern vein treatments are minimally invasive, safe, and highly effective. At Avis Vascular Centre, we specialise in three advanced options — Medical Glue Closure, Endovenous Laser Ablation (EVLA), and Radiofrequency Ablation (RFA). All three are walk-in/walk-out procedures, but each has its own strengths.

1. Medical Glue Closure – The Needle-and-Done Solution

How it works: Using a thin catheter, a specially formulated medical adhesive is placed inside the diseased vein. The glue seals the vein instantly, and blood flow naturally reroutes to healthier veins.

Why choose it:

  • No heat, no multiple injections
  • Usually no need for compression stockings
  • Resume normal activity almost immediately
  • Minimal discomfort during and after the procedure

Best for: Patients seeking the least invasive option, especially those sensitive to injections or who cannot wear compression stockings due to lifestyle or skin conditions.

2. Endovenous Laser Ablation (EVLA) – Precision with Proven Results

How it works: A laser fibre is inserted into the affected vein under ultrasound guidance. Laser energy is delivered to heat and seal the vein walls, closing it permanently.

Why choose it:

  • Over 20 years of clinical success worldwide
  • Excellent long-term closure rates above 95%
  • Quick recovery — usually within 24–48 hours
  • Highly precise for targeted treatment

Considerations: Requires local anaesthesia along the vein’s length and typically one week of compression stockings to optimise results.

Best for: Patients with large, straight veins where maximum precision is needed for complete closure.

3. Radiofrequency Ablation (RFA) – Gentle Heat, Lasting Relief

How it works: A fine catheter delivers controlled radiofrequency energy to the vein wall. The heat causes the vein to collapse and seal shut, while surrounding tissues remain protected.

Why choose it:

  • Less post-procedure discomfort than older heat-based methods
  • Procedure time usually under 45 minutes
  • Quick return to normal activities, often the next day

Considerations: Like EVLA, it requires local anaesthesia and short-term compression stockings.

Best for: Patients who want a comfortable thermal treatment with proven long-term results.

Choosing the Right Option

Your ideal treatment depends on the size and shape of your veins, your medical history, and your personal comfort preferences. Glue offers the ultimate convenience with no heat or stockings. Laser is ideal for larger, straighter veins needing precision. RFA provides a gentle heat-based solution with excellent patient comfort.

At Avis Vascular Centre, we use detailed ultrasound vein mapping to select the treatment that best suits you — ensuring safe, effective, and lasting results.

Embracing CLaCS Treatment for Chronic Venous Insufficiency

Do you find yourself battling with discomfort, swelling, or those dreaded varicose veins? If so, you’re not alone. Chronic Venous Insufficiency (CVI) affects countless individuals, causing not just physical discomfort but also affecting our confidence and daily lives.

But fear not, because there’s a revolutionary solution on the horizon: CLaCS treatment. 

CLaCS, or Cryo-Laser and Cryo-Sclerotherapy, has garnered significant attention in the medical community due to its promising efficacy in treating chronic venous insufficiency (CVI). Research studies have provided valuable insights into the effectiveness of CLaCS, demonstrating its ability to provide relief from CVI symptoms and improve patients’ overall vascular health. Let’s understand more about this innovative approach that’s changing the game for those struggling with CVI and several other vein problems.

What is CVI?

Chronic Venous Insufficiency (CVI) is a medical condition that occurs when the veins in the legs are unable to efficiently return blood back to the heart. Normally, one-way valves in the veins help to prevent blood from flowing backward, ensuring that it moves upward toward the heart. However, when these valves become weakened or damaged, blood can pool or flow backward, leading to CVI.

CVI can be a real nuisance, leading to complications like venous ulcers, skin changes, and even blood clots if left unchecked. That’s why it’s essential to seek effective management strategies. 

Cryo-Laser and Cryo-Sclerotherapy (CLaCS) – a cutting-edge treatment

CLaCS is transforming the way we address CVI. What sets CLaCS apart is its gentle yet powerful approach. 

Unlike traditional vein treatments that may involve invasive procedures and lengthy recovery times, CLaCS is minimally invasive. Cryo-Laser and Cryo-Sclerotherapy, stands out due to its unique blend of gentleness and potency in treating chronic venous insufficiency (CVI). This innovative approach combines cryo-sclerotherapy, which involves using a freezing agent to collapse diseased veins, with laser therapy to seal them shut. This dual-action method not only ensures thorough closure of problematic veins but also minimizes discomfort and promotes faster recovery for patients.

What is really exciting about CLaCS isn’t just its effectiveness – it’s the human touch it brings to the table. Say goodbye to the discomfort and embarrassment of varicose veins, and hello to newfound confidence and comfort. Because let’s face it, living with CVI can take a toll not just on our bodies but also on our spirits.

Picture this: after undergoing CLaCS treatment, you’ll not only experience relief from the physical symptoms but also a renewed sense of self-assurance. No more hiding your legs or feeling self-conscious in shorts or skirts. With CLaCS, you can embrace every moment with confidence, knowing that your veins are in good hands.

And the best part? CLaCS isn’t just a quick fix. It’s a long-lasting solution that provides sustained relief from CVI symptoms. By addressing the root cause of the issue and promoting proper blood flow, CLaCS helps prevent recurrence, allowing you to enjoy life to the fullest without worrying about those pesky veins.

So, if you’re tired of letting CVI hold you back, why not explore the possibilities with CLaCS? Consult with a compassionate vascular specialist who understands not just the science but also the human aspect of your journey. Together, you can embark on a path towards healthier, happier legs – and a brighter future ahead.

Getting Laser Treatment for Varicose Veins? Read This First!

If you have varicose veins and have decided to get them removed through the painless and minimally invasive endovenous laser ablation treatment procedure, it is best to know the preparations that you must do before undergoing the procedure and the steps that you must follow after the treatment process as well.

In this blog, we will recommend the best practices that will help you get optimal results from the varicose vein painless laser treatment and also share post-treatment protocols that will not only assist in faster recovery but also ensure the least chances of varicose vein recurrence. Stay with us till the end.

Preparations before the Treatment

During the physical examination in your consultation visit, if the vein specialist suspects that you have varicose veins, he/she will recommend a few examination checks to confirm the presence of varicose veins and check for their exact count and precise location.

The doctor will also ask for your medical history and check if you consume any blood thinners which will probably have to be stopped a few days before the laser treatment of varicose veins.

Before the endovenous laser treatment process, you must be hydrated so it is a good idea to drink plenty of fluids especially water. It is advised that you wear loose-fitting clothes to the hospital on the day of the procedure and carry your compression stockings along.

After the preliminary examination, the vein specialist will use injection for local anaesthesia in the affected area. You will remain awake during the procedure but not feel any pain or discomfort in the area that is being treated. As it might be a little tough for you to drive back home, it is advised to bring a companion (friend or relative) along.

Post-Treatment Care Instructions

Your vein specialist will explain all after-treatment guidelines to you in detail. Below is a summary of the post-laser surgery precautions:

  1. Monitor the incision – A few of you may experience minor bleeding and bruising from the incision. If you notice blood stains on the bandages, raise your legs and apply pressure on the incision. If this does not stop the excessive bleeding, contact your doctor.

    If you also witness minor swelling, apply ice on the incision for 15 minutes. A painkiller may be taken to reduce the discomfort. You may wash the incision with soap and water. Never use hydrogen peroxide or alcohol to clean the wound.

  2. Avoid strenuous activities – Do not lift heavy weights or perform any strenuous exercise for at least two weeks from the date of the laser treatment. You may go out for a brisk walk, 20 minute every day is good to ensure proper blood flow and fast-track the healing process.
  3. Take showers – Instead of soaking your legs in hot water, take showers in the first week after the treatment procedure. The water that you bathe with must only be warm and not hot.
  4. Do not sit or stand for long durations – Although you can do your everyday chores, join office, and get back to work soon after your laser surgery, you must avoid sitting or standing for long durations at a stretch. Moving around at frequent intervals aids in improving blood flow.
  5. Wear compression stockings – Compression stockings are support stockings that put additional pressure on the leg veins and thus promote blood flow back to the heart. You must wear compression stockings continuously for at least three days after the laser treatment or as recommended by your vein expert.
  6. Do not miss follow-up appointments – You must never miss your follow-up appointments with your vein specialist. He/She may call you over for ultrasounds checks to monitor the healing progress and to review your medications in a few days after the procedure, ensure to get your check-ups done in a timely manner.

Conclusion

Laser treatment is a quick procedure that is 100% safe and offers a faster recovery rate. To be able to achieve excellent results, always follow the above tips and tricks. Do not forget to speak to your vein specialist for any other precautions that you must take before and after the laser surgery of varicose veins.

Dr. Rajah V Koppala is the best interventional radiologist in Hyderabad, India and is renowned for his whopping high success rate of endovenous laser ablation procedures on varicose veins patients. In his more than two decades of medical practice as a vascular surgeon, he has completed over 12000 laser procedures. His patients are happy with his professionalism and totally satisfied with his unmatched medical assistance.

At Avis Vascular Centre, Dr. Rajah V Koppala and his team of vein specialists employ only the USFDA approved treatment procedures of laser treatment and follow all protocols of the American College of Phlebology. Dr. Rajah V Koppala and his team prioritize patient health and focus primarily on their satisfaction. They ensure the highest levels of comfort for patients of all age groups and have made special provisions for non-local patients with round-the-clock assistance for Mediclaim approvals from all leading national insurance agencies.

If you are worried about those swollen and enlarged veins that are visible to be bulging out from the skin surface and experience immense pain and discomfort from them, do not hesitate to schedule a consultation appointment with Dr. Rajah V Koppala at Avis Vascular Centre. We begin with a physical examination along with ultrasound scans to know if you will benefit from the laser treatment. For a thorough analysis and best-in-class laser treatment, book your consultation today!