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Glue-Based Varicose Vein Treatment: Safety & Results

Varicose veins — those enlarged, twisted veins often seen on the legs — are more than just a cosmetic concern. They can cause aching, swelling, heaviness, skin changes, and in severe cases, ulcers or clots. For many years, treatment options involved surgery or heat-based procedures like Endovenous Laser Ablation (EVLA) and Radiofrequency Ablation (RFA).

In recent years, glue-based varicose vein treatment, also called cyanoacrylate closure, has emerged as a modern, minimally invasive option. But is it safe? Let’s explore what it is, how it works, and what patients need to know.

How Glue-Based Treatment Works

The procedure uses a specially formulated medical adhesive delivered into the diseased vein via a thin catheter, guided by ultrasound. Once inside, the glue seals the vein walls together. Blood flow is instantly rerouted to healthy veins, and over time, the closed vein is absorbed naturally by the body.

Because it doesn’t use heat, glue closure avoids thermal injury to surrounding tissues and eliminates the need for multiple injections of tumescent anaesthesia along the vein. Most treatments take 20–30 minutes per vein, with patients walking out of the clinic shortly after.

Key Benefits of Glue-Based Treatment

  1. Virtually Pain-Free

A single tiny numbing injection is usually all that’s needed. Patients often describe the experience as “more comfortable than a blood test.”

  1. Same-Day Return to Routine

Whether you have a desk job, run a business, or manage a household, you can get treated in the morning and resume normal activities the very same day.

  1. No Extended Stocking Wear

In India’s warm climate, avoiding weeks of compression stockings is a major relief. In many glue cases, stockings are either not required or needed for just a short period.

  1. Small, Cosmetic-Friendly Entry Point

No surgical cuts or stitches — just a tiny puncture that typically heals without a visible mark.

  1. Works for Many Patient Profiles

Suitable for a wide range of vein anatomies, including those where a no-heat approach is preferred. It’s an excellent addition to the treatment choices available in India.

Is It Safe?

Glue-based closure is FDA-approved and has been used globally since 2011. The adhesive is a proven surgical material also used in closing wounds and controlling bleeding in delicate surgeries. When performed by trained vascular specialists under ultrasound guidance, it has an excellent safety record.

Potential Risks

While uncommon, mild inflammation (phlebitis), temporary tenderness, or rare allergic reactions to the adhesive can occur. These usually resolve quickly with simple medication.

Results You Can Expect

  • Treated veins gradually shrink and fade over weeks to months
  • Noticeable relief from heaviness, swelling, and discomfort within days
  • Long-lasting closure and improved leg appearance with minimal downtime

The Bottom Line

Glue-based varicose vein treatment is a safe, comfortable, and highly effective option for those seeking a quick recovery and lasting results. It complements other advanced treatments like EVLA and RFA, ensuring patients have choices tailored to their needs.

Why Glue Treatment Is Becoming Popular for Varicose Veins

Varicose veins are a common condition in India, affecting people across age groups and lifestyles. They occur when vein valves weaken, causing blood to pool and veins to enlarge. Symptoms may include heaviness, swelling, aching, night cramps, and skin changes. If left untreated, complications like ulcers or clot formation can occur.

Modern vascular medicine offers several highly effective, minimally invasive treatments — including Endovenous Laser Ablation (EVLA), Radiofrequency Ablation (RFA), and the newer medical glue-based closure. While each option has distinct advantages, glue-based treatment is drawing growing interest among Indian patients for its unique features.

What Is Glue-Based Treatment?

Also known as cyanoacrylate vein closure, this method uses a specially formulated medical adhesive delivered through a thin catheter into the affected vein. Guided by ultrasound, the glue seals the vein instantly. Blood is then naturally rerouted to healthy veins.

The procedure is quick, requires only a small numbing injection at the entry site, and allows most patients to walk out of the clinic within an hour.

Why It’s Gaining Popularity in India

  1. Comfort in a Warm Climate

In India’s warm and humid weather, wearing medical compression stockings after treatment can be challenging. Many glue procedures do not require extended stocking use, which appeals to patients who want a simpler recovery.

  1. Convenience for Busy Lifestyles

Whether it’s a corporate professional in Mumbai or a homemaker in Hyderabad, many patients prefer procedures with minimal disruption. Glue closure allows a quick return to daily routines — often on the same day — making it well-suited to fast-paced urban life.

  1. Minimal Injections

While all modern treatments are performed under local anaesthesia for comfort, glue closure usually needs only one numbing shot at the catheter entry point. Patients who are sensitive to multiple injections appreciate this streamlined approach.

  1. Suitability for a Broad Range of Patients

Glue closure is an excellent option for many patient profiles, including those with certain health conditions or anatomical considerations where a no-heat technique may be preferred. It complements other treatments, ensuring a wider choice for individual needs.

  1. Rising Awareness

Specialised vascular centres and patient education campaigns are helping more people learn about glue-based treatment. Social media, patient testimonials, and doctor-led awareness drives are boosting its visibility, especially in metropolitan and tier-2 cities.

How the Procedure Works

  1. Ultrasound Mapping – The affected vein is identified and assessed.
  2. Catheter Placement – A small puncture is made to introduce a thin catheter.
  3. Glue Delivery – The adhesive is placed in controlled amounts under ultrasound guidance.
  4. Vein Sealing – The vein closes instantly.
  5. Completion – The catheter is removed and a small dressing is applied.

The procedure typically takes 20–30 minutes per vein, and patients can walk immediately afterwards.

The Avis Vascular Centre Advantage

At Avis Vascular Centre, we offer the full range of advanced vein treatments, including glue closure, EVLA, and RFA. Our vascular specialists perform detailed ultrasound vein mapping to recommend the option best suited to each patient’s anatomy, lifestyle, and preferences. With state-of-the-art technology and a patient-first approach, we ensure safe, effective, and lasting results.

Whether you’re looking for a treatment that fits into your busy schedule, avoids prolonged use of compression stockings, or offers minimal injections, glue-based closure is proving to be a comfortable and effective solution for many patients in India. As awareness grows and access expands, its role in modern vein care is only set to increase.

Glue vs Laser vs RFA: Best Varicose Vein Treatment?

Varicose veins are more than a cosmetic issue — they are a medical condition that can cause aching, heaviness, swelling, cramps, skin discolouration, and, in advanced cases, ulcers or blood clots. If left untreated, the symptoms can worsen, affecting both health and quality of life.

The good news is that modern vein treatments are minimally invasive, safe, and highly effective. At Avis Vascular Centre, we specialise in three advanced options — Medical Glue Closure, Endovenous Laser Ablation (EVLA), and Radiofrequency Ablation (RFA). All three are walk-in/walk-out procedures, but each has its own strengths.

1. Medical Glue Closure – The Needle-and-Done Solution

How it works: Using a thin catheter, a specially formulated medical adhesive is placed inside the diseased vein. The glue seals the vein instantly, and blood flow naturally reroutes to healthier veins.

Why choose it:

  • No heat, no multiple injections
  • Usually no need for compression stockings
  • Resume normal activity almost immediately
  • Minimal discomfort during and after the procedure

Best for: Patients seeking the least invasive option, especially those sensitive to injections or who cannot wear compression stockings due to lifestyle or skin conditions.

2. Endovenous Laser Ablation (EVLA) – Precision with Proven Results

How it works: A laser fibre is inserted into the affected vein under ultrasound guidance. Laser energy is delivered to heat and seal the vein walls, closing it permanently.

Why choose it:

  • Over 20 years of clinical success worldwide
  • Excellent long-term closure rates above 95%
  • Quick recovery — usually within 24–48 hours
  • Highly precise for targeted treatment

Considerations: Requires local anaesthesia along the vein’s length and typically one week of compression stockings to optimise results.

Best for: Patients with large, straight veins where maximum precision is needed for complete closure.

3. Radiofrequency Ablation (RFA) – Gentle Heat, Lasting Relief

How it works: A fine catheter delivers controlled radiofrequency energy to the vein wall. The heat causes the vein to collapse and seal shut, while surrounding tissues remain protected.

Why choose it:

  • Less post-procedure discomfort than older heat-based methods
  • Procedure time usually under 45 minutes
  • Quick return to normal activities, often the next day

Considerations: Like EVLA, it requires local anaesthesia and short-term compression stockings.

Best for: Patients who want a comfortable thermal treatment with proven long-term results.

Choosing the Right Option

Your ideal treatment depends on the size and shape of your veins, your medical history, and your personal comfort preferences. Glue offers the ultimate convenience with no heat or stockings. Laser is ideal for larger, straighter veins needing precision. RFA provides a gentle heat-based solution with excellent patient comfort.

At Avis Vascular Centre, we use detailed ultrasound vein mapping to select the treatment that best suits you — ensuring safe, effective, and lasting results.

Ultimate Guide to VenaSeal® Glue Treatment for Varicose Veins

Varicose veins are swollen, twisted veins that often appear on the legs and feet. While they can be a cosmetic issue for some, for many, they lead to discomfort, aching, swelling, and even skin ulcers. Fortunately, modern medicine has introduced advanced, minimally invasive treatments — and one of the most revolutionary among them is VenaSeal®, a glue-based solution that’s transforming how varicose veins are managed.

What is VenaSeal®?

VenaSeal® is a non-thermal, non-tumescent, and minimally invasive treatment that uses a specially formulated medical adhesive (cyanoacrylate) to close diseased veins. Unlike traditional therapies like laser or radiofrequency ablation, which use heat, or sclerotherapy, which uses chemical irritation, VenaSeal® seals the vein shut with a safe, biocompatible glue.

Once the vein is closed, blood is naturally rerouted through healthier veins. Over time, the treated vein becomes fibrotic and is gradually absorbed by the body.

How is the Procedure Done?

The VenaSeal® procedure is performed under ultrasound guidance in a clinical setting and usually takes less than 30 minutes. Here’s what typically happens:

  1. The doctor maps the affected vein using ultrasound.
  2. A tiny catheter is inserted into the vein through a small puncture.
  3. The VenaSeal® adhesive is delivered in small amounts along the vein while pressure is applied to seal it.
  4. The catheter is removed, and a small bandage is applied.

No stitches, tumescent anaesthesia, or thermal devices are used — making this a relatively comfortable and quick procedure.

Benefits of VenaSeal®

Patients and doctors alike are increasingly choosing VenaSeal® for several compelling reasons:

  • No need for compression stockings after the procedure in most cases.
  • No heat or nerve injury risks, unlike thermal ablation methods.
  • Minimal bruising or discomfort, as there’s no tumescent anaesthetic injected.
  • No downtime — most patients return to normal activities the same day.
  • Cosmetically superior — no scars, burns, or pigmentation.
  • Clinically proven efficacy, with closure rates exceeding 90% in long-term studies.

Who Can Benefit from VenaSeal®?

VenaSeal® is ideal for patients with symptomatic chronic venous insufficiency (CVI) or visible varicose veins. It’s particularly suited for those who wish to avoid heat-based treatments or prolonged recovery. However, it may not be suitable for all types of vein conditions — a comprehensive venous ultrasound and consultation with a vascular specialist is crucial.

Is It Safe?

VenaSeal® is FDA-approved and has undergone extensive clinical testing worldwide. Side effects are rare and usually mild, such as temporary inflammation or tenderness at the puncture site. Since there’s no heat involved, the risk of nerve injury is significantly lower.

Final Thoughts

VenaSeal® represents a major advancement in the treatment of varicose veins — offering a fast, effective, and virtually painless option with excellent cosmetic outcomes. If you’re tired of living with leg pain, swelling, or unsightly veins, speak with a qualified vascular surgeon to find out if VenaSeal® is right for you. With just a few drops of medical adhesive, you could be on your way to healthier, more comfortable legs.