MUCORMYCOSIS

All around the world is in panic with covid19 pandemic and now as an add on to this situation there is a rare fungal infection called Mucormycosis which is shaking the entire

world again!!!

Let us now learn a few facts about this rare fungal infection

What is Mucormycosis?

Mucormycosis is a serious but rare fungal infection caused by a group of molds called

mucormycetes.This condition is commonly referred to as BLACK FUNGUS.

What is the mode of spread & who are at high risk?

These molds live throughout the environment. So, there is no particular source of contact though common sources of infections are from soil, damp walls on old buildings etc.
Mucormycosis mainly affects people who have health problems or take medicines that lower the body’s ability to fight germs and sickness. It most commonly affects the sinuses or the lungs after inhaling fungal spores from the air.It can also Occur on the skin after a cut, burn, or other type of skin injury.

SYMPTOMS
Depend on where in the body the fungus is growing:

RHINOCEREBRAL MUCORMYCOSIS:


• One-sided facial swelling
• Headache
• Nasal or sinus congestion
• Black lesions on nasal bridge or upper inside of mouth that quickly become more severe
• Fever

PULMONARY MUCORMYCOSIS:
• Fever
• Cough
• Chest pain
• Shortness of breath

CUTANEOUS MUCORMYCOSIS:
• Blisters or ulcers on the skin and the infected area may turn black.
Other symptoms include
• pain
• warmth
• excessive redness or swelling around a wound.


GASTROINTESTINAL MUCORMYCOSIS:
• Abdominal pain
• Nausea and vomiting
• Gastrointestinal bleeding

DISSEMINATED MUCORMYCOSIS:
Typically occurs in people who are already sick from other medical conditions, so it can be difficult to know which symptoms are related to mucormycosis. Patients with disseminated infection in the brain can develop mental status changes or coma.

Who are at high risk of developing
mucormycosis?
• AIDS
• Uncontrolled DM
• Lymphomas
• Kidney failure
• Organ transplant
• Long term usage of steroids


When to consult a doctor?
Mucormycosis is a condition which progresses rapidly & as it is a dreadful situation you need to consult the doctor as soon as you notice the above symptoms.

How do we treat mucormycosis?
Early recognition, diagnosis, and prompt administration of appropriate antifungal treatment
are important for improving outcomes for patients with mucormycosis.
We generally treat with the following
medications
• Amphotericin B,
• Posaconazole,
• Isavuconazole


As these are active against most mucormycetes.
Lipid formulations of amphotericin B are often used as first-line treatment. In addition, surgical debridement or resection of infected tissue is often necessary, particularly for rhinocerebral,cutaneous, and gastrointestinal infections.Control of the underlying immunocompromising condition should be attempted when possible.The efficacy of other treatments such as hyperbaric oxygen therapy is uncertain but have been
useful in certain Situations.


Conclusion:
As there are emerging cases of mucormycosis we need to know that the early diagnosis gives the better outcome.